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Introduction
The Free PSA test measures the proportion of prostate-specific antigen (PSA) in the blood that is not bound to proteins. This test is often used in conjunction with total PSA to assess the risk of prostate cancer, particularly in men with moderately elevated PSA levels. At Crossroads Urology, we utilize Free PSA testing as part of a comprehensive diagnostic strategy for prostate health.
Purpose
The Free PSA test is used to:
- Differentiate between prostate cancer and benign prostate conditions such as BPH or prostatitis.
- Refine cancer risk assessment in patients with elevated total PSA levels.
- Determine the need for further diagnostic procedures, such as a prostate biopsy.
Procedure
- A blood sample is drawn from a vein in the arm.
- The sample is analyzed in a laboratory to calculate the percentage of Free PSA relative to total PSA.
- Results are typically available within a few days.
Preparation
- Avoid ejaculation for 24-48 hours before the test, as it may temporarily alter PSA levels.
- Inform the provider of any recent prostate manipulations, such as biopsies or digital rectal exams.
- No fasting is required for this test.
Risks and Considerations
- The Free PSA test is safe and involves only the minor risks associated with blood draws, such as bruising or discomfort at the puncture site.
- Lower percentages of Free PSA are associated with a higher likelihood of prostate cancer, while higher percentages suggest benign conditions.
At Crossroads Urology, we interpret Free PSA results in combination with total PSA and other clinical factors to provide accurate risk assessments.
Results
- Results are expressed as a percentage.
- A lower Free PSA percentage (e.g., <10%) may indicate a higher risk of prostate cancer, warranting further investigation.
- Higher percentages (e.g., >25%) are more often associated with benign prostate conditions.
Conclusion
Free PSA testing is a valuable tool for refining prostate cancer risk assessment and avoiding unnecessary procedures. At Crossroads Urology, we integrate advanced testing with expert clinical judgment to deliver personalized care. Contact us today to learn more about Free PSA testing and schedule your evaluation.
